BDBM164529 US9067871, 28

SMILES Cn1cc(cn1)S(=O)(=O)NCCOc1ccc2CCC(N)C(Cc3ccc(Cl)cc3)c2c1

InChI Key InChIKey=YMXKRISQYPIPLQ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 164529   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
Abbvie Deutschland

US Patent
LigandPNGBDBM164529(US9067871, 28)
Affinity DataKi: <10nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetSodium- and chloride-dependent glycine transporter 1(Human)
Abbvie Deutschland

US Patent
LigandPNGBDBM164529(US9067871, 28)
Affinity DataIC50: 10nMAssay Description:[3H]-Glycine uptake into recombinant CHO cells expressing human GlyT1: Human GlyT1c expressing recombinant hGlyT1c5_CHO cells were plated at 20,000 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent