BDBM164639 US9067871, 116::US9067871, 117::US9067871, 118::US9067871, 119

SMILES Cn1cnc(c1)S(=O)(=O)NCCOc1ccc2CCC(C(Cc3ccccc3)c2c1)N1CCCC1

InChI Key InChIKey=QTUXMVZZQMHBAN-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 164639   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
Abbvie Deutschland

US Patent
LigandPNGBDBM164639(US9067871, 116 | US9067871, 117 | US9067871, 119 |...)
Affinity DataKi: <10nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetSodium- and chloride-dependent glycine transporter 1(Human)
Abbvie Deutschland

US Patent
LigandPNGBDBM164639(US9067871, 116 | US9067871, 117 | US9067871, 119 |...)
Affinity DataKi: <10nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetSodium- and chloride-dependent glycine transporter 1(Human)
Abbvie Deutschland

US Patent
LigandPNGBDBM164639(US9067871, 116 | US9067871, 117 | US9067871, 119 |...)
Affinity DataKi: <10nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetSodium- and chloride-dependent glycine transporter 1(Human)
Abbvie Deutschland

US Patent
LigandPNGBDBM164639(US9067871, 116 | US9067871, 117 | US9067871, 119 |...)
Affinity DataKi: <100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent