BDBM164765 US9067871, 241::US9067871, 242::US9067871, 246

SMILES CNC1CCc2ccc(OCCNS(=O)(=O)c3ccn(C)c3)cc2C1Cc1cc(F)cc(F)c1

InChI Key InChIKey=QBVQYBBXPXKGMD-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 164765   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
Abbvie Deutschland

US Patent
LigandPNGBDBM164765(US9067871, 241 | US9067871, 242 | US9067871, 246)
Affinity DataKi: <10nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetSodium- and chloride-dependent glycine transporter 1(Human)
Abbvie Deutschland

US Patent
LigandPNGBDBM164765(US9067871, 241 | US9067871, 242 | US9067871, 246)
Affinity DataKi: <10nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetSodium- and chloride-dependent glycine transporter 1(Human)
Abbvie Deutschland

US Patent
LigandPNGBDBM164765(US9067871, 241 | US9067871, 242 | US9067871, 246)
Affinity DataKi: <100nMAssay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent