BDBM166651 4-((4-(5-nitrothiophene-2-carboxamido)phenyl)amino)-4-oxobutanoic acid (10)

SMILES OC(=O)CCC(=O)Nc1ccc(NC(=O)c2ccc(s2)[N+]([O-])=O)cc1

InChI Key InChIKey=CNCBAAWCRTYXMY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 166651   

TargetDNA gyrase subunit B(Staphylococcus aureus)
Birla Institute of Technology

LigandPNGBDBM166651(4-((4-(5-nitrothiophene-2-carboxamido)phenyl)amino...)
Affinity DataIC50: 1.25E+4nMpH: 7.5Assay Description:Initially, equimolar quantities of about 0.5µM each of E. coli gyraseA and S. aureus gyraseB were incubated for a period of 45 min with salmon sperm ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Birla Institute of Technology

LigandPNGBDBM166651(4-((4-(5-nitrothiophene-2-carboxamido)phenyl)amino...)
Affinity DataIC50: 6.12E+3nMpH: 7.6 T: 2°CAssay Description:Supercoiling assay was performed using the commercially available kit (DNA gyrase supercoiling assay kit: SAS4001) from Inspiralis Pvt.limited, Norwi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed