BDBM16690 1,3,5-trisubstituted aromatic scaffold, 2b::1-N-[(2S)-1-amino-3-phenylpropan-2-yl]-3-N-[(1R)-1-(4-fluorophenyl)ethyl]-5-(N-methylmethanesulfonamido)benzene-1,3-dicarboxamide

SMILES C[C@@H](NC(=O)c1cc(cc(c1)C(=O)N[C@H](CN)Cc1ccccc1)N(C)S(C)(=O)=O)c1ccc(F)cc1

InChI Key InChIKey=YZEIFYCEDBCRSP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16690   

TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM16690(1-N-[(2S)-1-amino-3-phenylpropan-2-yl]-3-N-[(1R)-1...)
Affinity DataIC50: 5.90E+3nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed