BDBM16717 1-N-[1-hydroxy-3-(3-methoxyphenyl)propan-2-yl]-3-N-methyl-5-(N-methylmethanesulfonamido)benzene-1,3-dicarboxamide::5-Substituted isophthalamide, 3

SMILES CNC(=O)c1cc(cc(c1)C(=O)NC(CO)Cc1cccc(OC)c1)N(C)S(C)(=O)=O

InChI Key InChIKey=FCLBNUWJCDRNBW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16717   

TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM16717(1-N-[1-hydroxy-3-(3-methoxyphenyl)propan-2-yl]-3-N...)
Affinity DataIC50: 1.00E+5nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed