BDBM16737 N-(2-{4-[5-(1,2-dithiolan-3-yl)pentanoyl]piperazin-1-yl}-5-phenylphenyl)naphthalene-1-carboxamide::Naphthyl Compound, 6b

SMILES O=C(CCCCC1CCSS1)N1CCN(CC1)c1ccc(cc1NC(=O)c1cccc2ccccc12)-c1ccccc1

InChI Key InChIKey=AHMSLYTXWAPXRM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16737   

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16737(N-(2-{4-[5-(1,2-dithiolan-3-yl)pentanoyl]piperazin...)
Affinity DataIC50: 3.80E+3nMpH: 7.5 T: 2°CAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed