BDBM167449 US9073906, 183

SMILES CC1CN(CC(=O)NC2C3CC4CC2C[C@@](C4)(C3)C(N)=O)S(=O)(=O)N(C1)c1c(Cl)cc(cc1Cl)C(F)(F)F

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 167449   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM167449(US9073906, 183)
Affinity DataIC50: 4.80nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM167449(US9073906, 183)
Affinity DataIC50: 1.00E+4nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
Go to US Patent