BDBM16748 Coumarin Compound, 11b::tert-butyl 4-{2-[(2-oxo-2H-chromene-3-)amido]-4-phenylphenyl}piperazine-1-carboxylate

SMILES CC(C)(C)OC(=O)N1CCN(CC1)c1ccc(cc1NC(=O)c1cc2ccccc2oc1=O)-c1ccccc1

InChI Key InChIKey=BRJABFAZOKDLSK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16748   

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16748(tert-butyl 4-{2-[(2-oxo-2H-chromene-3-)amido]-4-ph...)
Affinity DataIC50: 1.00E+4nMAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed