BDBM167925 (1-(2-Chlorobenzyl)-1H-1,2,3-triazol-4-yl)methyl 2-(2-oxo-2H-chromen-4-yloxy)acetate (8k)

SMILES Clc1ccccc1Cn1cc(COC(=O)COc2cc(=O)oc3ccccc23)nn1

InChI Key InChIKey=SIOZGCLDAYJXIF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 167925   

TargetAcetylcholinesterase(Electric eel)
Tehran University of Medical Sciences

LigandPNGBDBM167925((1-(2-Chlorobenzyl)-1H-1,2,3-triazol-4-yl)methyl 2...)
Affinity DataIC50: 180nMpH: 8.0Assay Description:The target compounds were dissolved in a mixture of 1 mL DMSO and 9 mL methanol and diluted in 0.1 M KH2PO4/K2HPO4 buffer (pH 8.0) to obtain final co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Tehran University of Medical Sciences

LigandPNGBDBM167925((1-(2-Chlorobenzyl)-1H-1,2,3-triazol-4-yl)methyl 2...)
Affinity DataIC50: 5.00E+4nMpH: 8.0Assay Description:The target compounds were dissolved in a mixture of 1 mL DMSO and 9 mL methanol and diluted in 0.1 M KH2PO4/K2HPO4 buffer (pH 8.0) to obtain final co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Tehran University of Medical Sciences

LigandPNGBDBM167925((1-(2-Chlorobenzyl)-1H-1,2,3-triazol-4-yl)methyl 2...)
Affinity DataIC50: 180nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured after 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed