BDBM167950 1-(4-(4-Nitrophenyl)piperazin-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3f)

SMILES OC(COc1ncnc2ccccc12)CN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=LDYXRYLRGPOXCN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 167950   

TargetVascular endothelial growth factor receptor 2(Human)
Nanjing University

LigandPNGBDBM167950(1-(4-(4-Nitrophenyl)piperazin-1-yl)-3-(quinazolin-...)
Affinity DataIC50: 16.5nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Nanjing University

LigandPNGBDBM167950(1-(4-(4-Nitrophenyl)piperazin-1-yl)-3-(quinazolin-...)
Affinity DataIC50: 109nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Nanjing University

LigandPNGBDBM167950(1-(4-(4-Nitrophenyl)piperazin-1-yl)-3-(quinazolin-...)
Affinity DataIC50: 248nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Nanjing University

LigandPNGBDBM167950(1-(4-(4-Nitrophenyl)piperazin-1-yl)-3-(quinazolin-...)
Affinity DataIC50: 382nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed