BDBM167958 1-(4-Benzylpiperazin-1-yl)-3-(quinazolin-4-yloxy)propan-2-ol (3n)

SMILES OC(COc1ncnc2ccccc12)CN1CCN(Cc2ccccc2)CC1

InChI Key InChIKey=GJRDMRRBRLWIMA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 167958   

TargetVascular endothelial growth factor receptor 2(Human)
Nanjing University

LigandPNGBDBM167958(1-(4-Benzylpiperazin-1-yl)-3-(quinazolin-4-yloxy)p...)
Affinity DataIC50: 52.2nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Nanjing University

LigandPNGBDBM167958(1-(4-Benzylpiperazin-1-yl)-3-(quinazolin-4-yloxy)p...)
Affinity DataIC50: 435nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Nanjing University

LigandPNGBDBM167958(1-(4-Benzylpiperazin-1-yl)-3-(quinazolin-4-yloxy)p...)
Affinity DataIC50: 444nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Nanjing University

LigandPNGBDBM167958(1-(4-Benzylpiperazin-1-yl)-3-(quinazolin-4-yloxy)p...)
Affinity DataIC50: 219nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed