BDBM170190 US9079902, 21

SMILES Cn1cc(-c2ccc(cc2-c2cn[nH]c2)C(F)(F)F)c2ccc(cc12)S(=O)(=O)Nc1ncns1

InChI Key InChIKey=NVBFTRZZWVPMOO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 170190   

LigandPNGBDBM170190(US9079902, 21)
Affinity DataIC50: 37.5nMAssay Description:293 cells stably transfected with either Nav 1.7 or with Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details
Go to US Patent

LigandPNGBDBM170190(US9079902, 21)
Affinity DataIC50: 1.00E+4nMAssay Description:293 cells stably transfected with either Nav 1.7 or with Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated ele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details
Go to US Patent

LigandPNGBDBM170190(US9079902, 21)
Affinity DataIC50: 38nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells by PatchXpress methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM170190(US9079902, 21)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Nav1.5 (unknown origin) expressed in HEK293 cells by IonWorks patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed