BDBM17045 2-[(3E)-2-oxo-5-sulfamoyl-2,3-dihydro-1H-indol-3-ylidene]-2-(1H-pyrrol-2-yl)acetamide::Indolinone based inhibitor, 4f

SMILES NC(=O)C(=C1\C(=O)Nc2ccc(cc12)S(N)(=O)=O)\c1ccc[nH]1

InChI Key InChIKey=GDTUCINIGAXVNH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17045   

Target3-phosphoinositide-dependent protein kinase 1(Human)
Berlex Biosciences

LigandPNGBDBM17045(2-[(3E)-2-oxo-5-sulfamoyl-2,3-dihydro-1H-indol-3-y...)
Affinity DataIC50: 3.90E+3nMAssay Description:The coupled assay can detect inhibitors of AKT2 activation, as well as direct inhibitors of PDK1 or AKT2. Inactive AKT2 is activated in situ by incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2007
Entry Details Article
PubMed