BDBM171816 US9085576, 2b-B::US9085576, 2b-rac
SMILES COc1cnc(cn1)C(=O)Nc1ccc(F)c(c1)[C@]1(C)N=C(N)O[C@@H]2C[C@H]12
InChI Key InChIKey=LUOFRFUNXXGHFC-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 171816
Affinity DataIC50: 605nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
Affinity DataIC50: 4.12E+4nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Affinity DataIC50: 4.28E+4nMpH: 3.5Assay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.13E+4nMpH: 3.5Assay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair