BDBM172465 US9090628, 108

SMILES CC(C)n1ncnc1-c1cn2CCOc3ccc(CN4CCN(CC4)C(C)(C)C)cc3-c2n1

InChI Key InChIKey=MBNYACZBQVCQMH-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 172465   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Genentech

US Patent

LigandBDBM172465(US9090628, 108)Copy SMILESCopy InChI

Affinity DataIC50: 2.46nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Genentech

US Patent

LigandBDBM172465(US9090628, 108)Copy SMILESCopy InChI

Affinity DataKi:  2.5nMAssay Description:Binding affinity to PI3Kdelta (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/7/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL