BDBM172637 US9090628, 297

SMILES CC(C)n1nc(C)nc1-c1cn2CCOc3cc(F)c(cc3-c2n1)[C@H](C)N1CCN(CC1)C(C)(C)C

InChI Key InChIKey=XLJFYTCFZPOLIV-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 172637   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Genentech

US Patent

LigandBDBM172637(US9090628, 297)Copy SMILESCopy InChI

Affinity DataIC50: 2.42nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/21/2016
Entry Details
Copy Entry DOIGo to US Patent

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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Genentech

US Patent

LigandBDBM172637(US9090628, 297)Copy SMILESCopy InChI

Affinity DataKi:  2.40nMAssay Description:Binding affinity to PI3Kdelta (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/7/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL