BDBM17313 (1S)-1-{4-[(2,4-difluorobenzene)sulfonamido]cyclohexyl}-2-[(3S)-3-fluoropyrrolidin-1-yl]-2-oxoethan-1-aminium::cyclohexylglycine derived inhibitor, 6

SMILES [NH3+][C@@H](C1CCC(CC1)NS(=O)(=O)c1ccc(F)cc1F)C(=O)N1CC[C@H](F)C1

InChI Key InChIKey=QTZTUCOZZMQUFY-UHFFFAOYSA-O

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 17313   

TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM17313((1S)-1-{4-[(2,4-difluorobenzene)sulfonamido]cycloh...)
Affinity DataIC50: 48nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

LigandPNGBDBM17313((1S)-1-{4-[(2,4-difluorobenzene)sulfonamido]cycloh...)
Affinity DataIC50: 990nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

LigandPNGBDBM17313((1S)-1-{4-[(2,4-difluorobenzene)sulfonamido]cycloh...)
Affinity DataIC50: 2.70E+3nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2007
Entry Details Article
PubMed