BDBM17317 (2S,3S)-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxo-3-(4-{[4-(trifluoromethoxy)benzene]sulfonamido}cyclohexyl)butan-2-aminium::cyclohexylalanine derived inhibitor, 19

SMILES C[C@H]([C@H]([NH3+])C(=O)N1CC[C@H](F)C1)C1CCC(CC1)NS(=O)(=O)c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=PGBZOCWEVKURAI-UHFFFAOYSA-O

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 17317   

TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM17317((2S,3S)-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxo-3-(...)
Affinity DataIC50: 440nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

LigandPNGBDBM17317((2S,3S)-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxo-3-(...)
Affinity DataIC50: 1.10E+4nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

LigandPNGBDBM17317((2S,3S)-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxo-3-(...)
Affinity DataIC50: 2.60E+4nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2007
Entry Details Article
PubMed