BDBM17472 1,2,3-triazole analogue, 28::4-(1H-1,2,3-triazol-5-yl)pyridine

SMILES c1[nH]nnc1-c1ccncc1

InChI Key InChIKey=KEFBRERBEDJOQZ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 17472   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM17472(4-(1H-1,2,3-triazol-5-yl)pyridine | 1,2,3-triazole...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant IDO expressed in Escherichia coli BL21 AIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM17472(4-(1H-1,2,3-triazol-5-yl)pyridine | 1,2,3-triazole...)
Affinity DataIC50: 8.50E+4nMpH: 6.5Assay Description:Inhibition of human recombinant N-terminal His-tagged IDO1 (Ala2 to Gly403) overexpressed in Escherichia coli BL21 at pH 6.5 after 60 mins by HPLC an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM17472(4-(1H-1,2,3-triazol-5-yl)pyridine | 1,2,3-triazole...)
Affinity DataKi: >1.00E+3nM ΔG°: >-8.10kcal/molepH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed