BDBM175406 2-[3-cyano-6-methyl-4,6-bis(3-methylphenyl)-1,2,5,6-tetrahydropyridin-2-ylidene]propanedinitrile (5c)

SMILES [#6]-c1cccc(c1)-[#6]-1=[#6](C#N)\[#6](-[#7]C([#6])([#6]-1)c1cccc(-[#6])c1)=[#6](/C#N)C#N

InChI Key InChIKey=CQIOAKCSTUUZTA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 175406   

TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandPNGBDBM175406(2-[3-cyano-6-methyl-4,6-bis(3-methylphenyl)-1,2,5,...)
Affinity DataIC50: 5.21E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandPNGBDBM175406(2-[3-cyano-6-methyl-4,6-bis(3-methylphenyl)-1,2,5,...)
Affinity DataIC50: 3.59E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed