BDBM175407 2-[3-cyano-4,6-bis(4-fluorophenyl)-6-methyl-1,2,5,6-tetrahydropyridin-2-ylidene]propanedinitrile (5d)

SMILES [#6]C1([#6]-[#6](=[#6](C#N)\[#6](-[#7]1)=[#6](/C#N)C#N)-c1ccc(F)cc1)c1ccc(F)cc1

InChI Key InChIKey=ZVJPXNYGGKYHJR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 175407   

TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandPNGBDBM175407(2-[3-cyano-4,6-bis(4-fluorophenyl)-6-methyl-1,2,5,...)
Affinity DataIC50: 1.19E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandPNGBDBM175407(2-[3-cyano-4,6-bis(4-fluorophenyl)-6-methyl-1,2,5,...)
Affinity DataIC50: 5.52E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed