BDBM175415 2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-bis(4'/4''-fluorophenyl)-1,2,5,6-tetrahydronicotinonitrile (2d)

SMILES CC1(CC(=C(C#N)C(N1)=C(C#N)c1nnn[nH]1)c1ccc(F)cc1)c1ccc(F)cc1

InChI Key InChIKey=HKWCMBRMDOHQAQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 175415   

TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandPNGBDBM175415(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50: 2.01E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandPNGBDBM175415(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50: 3.88E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed