BDBM175417 2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-bis(3'/3''-methoxyphenyl)-1,2,5,6-tetrahydronicotinonitrile (2f)

SMILES COc1cccc(c1)C1=C(C#N)C(NC(C)(C1)c1cccc(OC)c1)=C(C#N)c1nnn[nH]1

InChI Key InChIKey=VFVRAVZCYOJZTA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 175417   

TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandPNGBDBM175417(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50: 5.11E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandPNGBDBM175417(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50: 3.92E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed