BDBM175418 2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-bis(2'/2''-methoxyphenyl)-1,2,5,6-tetrahydronicotinonitrile (2g)

SMILES COc1ccccc1C1=C(C#N)C(NC(C)(C1)c1ccccc1OC)=C(C#N)c1nnn[nH]1

InChI Key InChIKey=XMRMLAOVUHZLII-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 175418   

TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandPNGBDBM175418(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50: 2.03E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandPNGBDBM175418(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50: 290nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed