BDBM17719 2,3-Diarylfuro[2,3-b]pyridine-4-amine, 15::2-{4-[2-(1H-imidazol-1-yl)ethoxy]phenyl}-3-phenyl-N-[2-(piperazin-1-yl)ethyl]furo[2,3-b]pyridin-4-amine

SMILES C(CN1CCNCC1)Nc1ccnc2oc(c(-c3ccccc3)c12)-c1ccc(OCCn2ccnc2)cc1

InChI Key InChIKey=WYNDNQIGGGWABE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 17719   

LigandPNGBDBM17719(2-{4-[2-(1H-imidazol-1-yl)ethoxy]phenyl}-3-phenyl-...)
Affinity DataIC50: 160nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

LigandPNGBDBM17719(2-{4-[2-(1H-imidazol-1-yl)ethoxy]phenyl}-3-phenyl-...)
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
Amgen

LigandPNGBDBM17719(2-{4-[2-(1H-imidazol-1-yl)ethoxy]phenyl}-3-phenyl-...)
Affinity DataIC50: 84nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
LigandPNGBDBM17719(2-{4-[2-(1H-imidazol-1-yl)ethoxy]phenyl}-3-phenyl-...)
Affinity DataIC50: 25nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed