BDBM17721 2,3-Diarylfuro[2,3-b]pyridine-4-amine, 17::3-phenyl-N-[2-(piperazin-1-yl)ethyl]-2-{4-[2-(piperidin-1-yl)ethoxy]phenyl}furo[2,3-b]pyridin-4-amine

SMILES C(CN1CCNCC1)Nc1ccnc2oc(c(-c3ccccc3)c12)-c1ccc(OCCN2CCCCC2)cc1

InChI Key InChIKey=ZMWKUKIYVSUWAS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 17721   

LigandPNGBDBM17721(3-phenyl-N-[2-(piperazin-1-yl)ethyl]-2-{4-[2-(pipe...)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

LigandPNGBDBM17721(3-phenyl-N-[2-(piperazin-1-yl)ethyl]-2-{4-[2-(pipe...)
Affinity DataIC50: 29nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
Amgen

LigandPNGBDBM17721(3-phenyl-N-[2-(piperazin-1-yl)ethyl]-2-{4-[2-(pipe...)
Affinity DataIC50: 120nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed
LigandPNGBDBM17721(3-phenyl-N-[2-(piperazin-1-yl)ethyl]-2-{4-[2-(pipe...)
Affinity DataIC50: 71nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2007
Entry Details Article
PubMed