BDBM177218 US9120749, 584::US9120749, 585

SMILES Oc1c(Cl)cc(cc1Cl)-c1ccc2ncc(C(=O)C3CC3)c(N[C@H]3CC[C@H](CN4CCCC4)CC3)c2c1

InChI Key InChIKey=OFTNLVBTNHHAJV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 177218   

TargetMaternal embryonic leucine zipper kinase(Human)
Oncotherapy Science

US Patent
LigandPNGBDBM177218(US9120749, 585 | US9120749, 584)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
Go to US Patent

TargetMaternal embryonic leucine zipper kinase(Human)
Oncotherapy Science

US Patent
LigandPNGBDBM177218(US9120749, 585 | US9120749, 584)
Affinity DataIC50: 1.40nMpH: 7.4 T: 2°CAssay Description:MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
Go to US Patent