BDBM177761 US9120785, Example 2 racemic mixture

SMILES CCC(O)([C@H]1CC[C@@H](CC1)C(N)=O)c1ncc(s1)-c1cc(C)cc(Nc2cc(ccn2)C2CC2)n1

InChI Key InChIKey=IRFBGBVPRKEVLP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 177761   

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM177761(US9120785, Example 2 racemic mixture)
Affinity DataIC50: 3.10nMpH: 7.5 T: 2°CAssay Description:Homogeneous Time-Resolved Fluorescence (HTRF) assay for the recombinant human Syk enzyme: A recombinant GST-hSyk fusion protein was used to measure p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
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