BDBM177766 US9120785, Example 14-2

SMILES CCCCOC(=O)C1CCC(CC1)C(C)(O)c1ncc(s1)-c1cc(C)cc(Nc2cc(OC)ccn2)n1

InChI Key InChIKey=CTJTYONQBNWOTO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 177766   

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM177766(US9120785, Example 14-2)
Affinity DataIC50: 219nMpH: 7.5 T: 2°CAssay Description:Homogeneous Time-Resolved Fluorescence (HTRF) assay for the recombinant human Syk enzyme: A recombinant GST-hSyk fusion protein was used to measure p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent