BDBM177767 US9120785, Example 14-4

SMILES Cc1cc(Nc2cc(ccn2)C(F)F)nc(c1)-c1cnc(s1)C(C)(O)C1CCC(CC1)C(O)=O

InChI Key InChIKey=XWXQHPYLTTZSEL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 177767   

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM177767(US9120785, Example 14-4)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:Homogeneous Time-Resolved Fluorescence (HTRF) assay for the recombinant human Syk enzyme: A recombinant GST-hSyk fusion protein was used to measure p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
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