BDBM17803 benzimidazole-urea, 31::methyl N-(6-{[5-({[2-fluoro-5-(trifluoromethyl)phenyl]carbamoyl}amino)pyridin-2-yl]oxy}-1H-1,3-benzodiazol-2-yl)carbamate

SMILES COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cn3)cc2[nH]1

InChI Key InChIKey=VSMMGESTZLCGTL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17803   

LigandPNGBDBM17803(methyl N-(6-{[5-({[2-fluoro-5-(trifluoromethyl)phe...)
Affinity DataIC50: 16nMAssay Description:The assay uses purified GST-Tie-2 or GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium cryptate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Gsk

LigandPNGBDBM17803(methyl N-(6-{[5-({[2-fluoro-5-(trifluoromethyl)phe...)
Affinity DataIC50: 20nMpH: 7.4 T: 2°CAssay Description:The assay uses purified GST-Tie-2 or GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium cryptate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed