BDBM17886 3-{[(1S,5R)-3-{2-[(tert-butylcarbamoyl)amino]-3,3-dimethylbutanoyl}-6,6-dichloro-3-azabicyclo[3.1.0]hexan-2-yl]formamido}-4-cyclobutyl-2-oxobutanamide::Ketoamide inhibitor, 23

SMILES CC(C)(C)NC(=O)NC(C(=O)N1C[C@H]2[C@@H](C1C(=O)NC(CC1CCC1)C(=O)C(N)=O)C2(Cl)Cl)C(C)(C)C

InChI Key InChIKey=QHUFHOWZHGDXDX-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17886   

TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17886(3-{[(1S,5R)-3-{2-[(tert-butylcarbamoyl)amino]-3,3-...)
Affinity DataKi:  19nMAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed