BDBM17893 3-{[(1R,5S)-3-{2-[(tert-butylcarbamoyl)amino]-3-methylbutanoyl}-6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2-yl]formamido}-4-cyclopropyl-2-oxobutanamide::Ketoamide inhibitor, 29

SMILES CC(C)C(NC(=O)NC(C)(C)C)C(=O)N1C[C@H]2[C@@H](C1C(=O)NC(CC1CC1)C(=O)C(N)=O)C2(C)C

InChI Key InChIKey=JETFGTQZGKPRJS-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17893   

TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM17893(3-{[(1R,5S)-3-{2-[(tert-butylcarbamoyl)amino]-3-me...)
Affinity DataKi:  100nMAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed