BDBM179078 US9126931, 847

SMILES CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1N1CCC(CC1)NC1CCCCC1

InChI Key InChIKey=WADOFXPNMMELJF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 179078   

TargetALK tyrosine kinase receptor(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM179078(US9126931, 847)
Affinity DataIC50: 1.89nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details
Go to US Patent