BDBM17954 (3S,4R)-4-(4-{3-[(2-methoxyphenyl)methoxy]propoxy}phenyl)-N-(1,2,3,4-tetrahydroquinolin-7-ylmethyl)piperidin-3-amine::amino-aryl-piperidine-based compound, 19::mixture of cis isomers

SMILES COc1ccccc1COCCCOc1ccc(cc1)[C@H]1CCNC[C@H]1NCc1ccc2CCCNc2c1

InChI Key InChIKey=KKXYEMLRFDXQTG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17954   

TargetRenin(Human)
Pfizer

LigandPNGBDBM17954(mixture of cis isomers | (3S,4R)-4-(4-{3-[(2-metho...)
Affinity DataIC50: 255nMpH: 7.4 T: 2°CAssay Description:The renin assay utilized a tandem Green Flourescent Protein (tGFP) substrate that was hydrolyzed by human rennin. The tGFP substrate contained a nine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2007
Entry Details Article
PubMed