BDBM17958 6-({[(3S,4R)-4-(4-{3-[(2-methoxyphenyl)methoxy]propoxy}phenyl)piperidin-3-yl]amino}methyl)naphthalene-1-carboxylic acid::amino-aryl-piperidine-based compound, 23::mixture of cis isomers

SMILES COc1ccccc1COCCCOc1ccc(cc1)[C@H]1CCNC[C@H]1NCc1ccc2c(cccc2c1)C(O)=O

InChI Key InChIKey=VUCTZMWYJWRKJI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17958   

TargetRenin(Human)
Pfizer

LigandPNGBDBM17958(6-({[(3S,4R)-4-(4-{3-[(2-methoxyphenyl)methoxy]pro...)
Affinity DataIC50: 2.60E+3nMpH: 7.4 T: 2°CAssay Description:The renin assay utilized a tandem Green Flourescent Protein (tGFP) substrate that was hydrolyzed by human rennin. The tGFP substrate contained a nine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2007
Entry Details Article
PubMed