BDBM18199 1-benzyl-9-(trifluoromethyl)-1H,2H,3H,6H,7H-quinolino[7,6-b][1,4]oxazin-7-one::7H-[1,4]Oxazino[3,2-g]quinolin-7-one based compound, 12b

SMILES FC(F)(F)c1cc(=O)[nH]c2cc3OCCN(Cc4ccccc4)c3cc12

InChI Key InChIKey=MOROQHBVBKVSID-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18199   

TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM18199(1-benzyl-9-(trifluoromethyl)-1H,2H,3H,6H,7H-quinol...)
Affinity DataKi:  206nM ΔG°:  -9.48kcal/mole IC50: 224nMpH: 7.4 T: 2°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2007
Entry Details Article
PubMed