BDBM18203 1,3-diethyl-9-(trifluoromethyl)-1H,2H,3H,6H,7H-quinolino[7,6-b][1,4]oxazin-7-one::7H-[1,4]Oxazino[3,2-g]quinolin-7-one based compound, 10j

SMILES CCC1CN(CC)c2cc3c(cc(=O)[nH]c3cc2O1)C(F)(F)F

InChI Key InChIKey=LLGNUOUFJSRIQB-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18203   

TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM18203(1,3-diethyl-9-(trifluoromethyl)-1H,2H,3H,6H,7H-qui...)
Affinity DataKi:  34nM ΔG°:  -10.6kcal/mole EC50:  31nMpH: 7.4 T: 2°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2007
Entry Details Article
PubMed