BDBM18205 (3S)-3-methyl-1-(2,2,2-trifluoroethyl)-9-(trifluoromethyl)-1H,2H,3H,6H,7H-quinolino[7,6-b][1,4]oxazin-7-one::7H-[1,4]Oxazino[3,2-g]quinolin-7-one based compound, (+) 10h

SMILES C[C@H]1CN(CC(F)(F)F)c2cc3c(cc(=O)[nH]c3cc2O1)C(F)(F)F

InChI Key InChIKey=PLVSLGFGXYLLNA-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18205   

TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM18205((3S)-3-methyl-1-(2,2,2-trifluoroethyl)-9-(trifluor...)
Affinity DataKi:  75nM ΔG°:  -10.1kcal/mole EC50:  44nMpH: 7.4 T: 2°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2007
Entry Details Article
PubMed