BDBM18221 (15R)-7-(trifluoromethyl)-17-oxa-4,11-diazatetracyclo[8.7.0.0^{3,8}.0^{11,15}]heptadeca-1,3(8),6,9-tetraen-5-one::7H-[1,4]Oxazino[3,2-g]quinolin-7-one based compound, (R)-27

SMILES FC(F)(F)c1cc(=O)[nH]c2cc3OC[C@H]4CCCN4c3cc12

InChI Key InChIKey=SGECBUYSUSBIRA-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18221   

TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM18221((15R)-7-(trifluoromethyl)-17-oxa-4,11-diazatetracy...)
Affinity DataKi:  27nM EC50:  26nMAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2007
Entry Details Article
PubMed