BDBM182974 US9150544, 8

SMILES COc1cc2c(N)nccc2cc1C[C@@H](N1CC[C@H](NS(=O)(=O)c2cnc(s2)N(C)C)C1=O)C(=O)OCC(C)C

InChI Key InChIKey=DSVIVCYXVBEWMO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 182974   

TargetCoagulation factor IX(Human)
Sanofi

US Patent
LigandPNGBDBM182974(US9150544, 8)
Affinity DataIC50: 1.60E+3nMAssay Description:The compounds according to the invention are tested in a range of concentrations (4.9 nM to 5 µM final) and deposited in a proportion of 25 µl per we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
Go to US Patent

TargetCoagulation factor X(Human)
Sanofi

US Patent
LigandPNGBDBM182974(US9150544, 8)
Affinity DataIC50: 100nMpH: 7.0Assay Description:The compounds according to the invention are tested in a range of concentrations (10pM to 10 µM final) in assay buffer (50 mM TRIS, 100 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
Go to US Patent