BDBM18322 (2S,4S,5S,7S)-5-amino-N-(2-carbamoylethyl)-4-hydroxy-7-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-8-methyl-2-(propan-2-yl)nonanamide::2,7-dialkyl-substituted 8-phenyl-octanecarboxamide, 30

SMILES COCCCOc1cc(C[C@@H](C[C@H](N)[C@@H](O)C[C@@H](C(C)C)C(=O)NCCC(N)=O)C(C)C)ccc1OC

InChI Key InChIKey=ZMXQABNZQRBOJN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18322   

TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18322((2S,4S,5S,7S)-5-amino-N-(2-carbamoylethyl)-4-hydro...)
Affinity DataIC50: 1nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed