BDBM1852 3-[(2-tert-Butylphenyl)sulfanyl]-5,6-dihydro-4-hydroxy-6-phenyl-6-(2-phenylethyl)-2H-pyran-2-one::3-[(2-tert-butylphenyl)sulfanyl]-4-hydroxy-6-phenyl-6-(2-phenylethyl)-5,6-dihydro-2H-pyran-2-one::4-Hydroxy-5,6-dihydropyrone deriv. 43

SMILES CC(C)(C)c1ccccc1SC1C(=O)CC(CCc2ccccc2)(OC1=O)c1ccccc1

InChI Key InChIKey=LARFIMFSCCGLFG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1852   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM1852(3-[(2-tert-butylphenyl)sulfanyl]-4-hydroxy-6-pheny...)
Affinity DataIC50: 3nMAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2004
Entry Details Article
PubMed