BDBM18547 7-[(2-methylbutan-2-yl)amino]-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one::alkylamino-2-quinolinone, 9g

SMILES CCC(C)(C)Nc1ccc2c(cc(=O)[nH]c2c1)C(F)(F)F

InChI Key InChIKey=RHOGPSSOKUGEQO-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18547   

TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM18547(7-[(2-methylbutan-2-yl)amino]-4-(trifluoromethyl)-...)
Affinity DataKi:  110nM ΔG°:  -9.87kcal/mole IC50: 209nMpH: 7.4 T: 2°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2007
Entry Details Article
PubMed