BDBM18597 2,2,2-trifluoro-N-[2-oxo-4-(trifluoromethyl)-1,2-dihydroquinolin-6-yl]-N-(2,2,2-trifluoroethyl)acetamide::6-bisalkylamino-2-quinolinone, 6v

SMILES FC(F)(F)CN(C(=O)C(F)(F)F)c1ccc2[nH]c(=O)cc(c2c1)C(F)(F)F

InChI Key InChIKey=IHNWDWNUQKPNJK-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18597   

TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM18597(2,2,2-trifluoro-N-[2-oxo-4-(trifluoromethyl)-1,2-d...)
Affinity DataKi:  1.00E+3nM IC50: 4.10nM EC50:  22nMAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2007
Entry Details Article
PubMed