BDBM186086 US9163012, 4

SMILES O[C@@]12CC3CC(C1)[C@H](OC(=O)N1CC[C@H](C1)Oc1ccc(cn1)C(F)(F)F)C(C3)C2

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 186086   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM186086(US9163012, 4)
Affinity DataIC50: 2.63nMT: 2°CAssay Description:Inhibition of microsomal preparations of 11.beta.-HSDl by compounds of the present invention, as described essentially previously (K. Solly, SS Mundt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent