BDBM18612 6-bisalkylamino-2-quinolinone, 8c::6-{[(2R)-1-chloropropan-2-yl](2,2,2-trifluoroethyl)amino}-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one

SMILES C[C@H](CCl)N(CC(F)(F)F)c1ccc2[nH]c(=O)cc(c2c1)C(F)(F)F

InChI Key InChIKey=AUIQVMLZIOYPBH-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18612   

TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

LigandPNGBDBM18612(6-{[(2R)-1-chloropropan-2-yl](2,2,2-trifluoroethyl...)
Affinity DataKi:  5.40nM EC50:  3.70nMAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2007
Entry Details Article
PubMed