BDBM186426 US9163021, 230::US9163021, 84

SMILES CC(CO)n1cc(C(=O)c2cc(NC(=O)Cc3ccc(cc3)C(F)(F)F)ccn2)c2cnccc12

InChI Key InChIKey=CRJGVCIGPRPYOO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 186426   

TargetHigh affinity nerve growth factor receptor(Human)
Pfizer

US Patent
LigandPNGBDBM186426(US9163021, 84 | US9163021, 230)
Affinity DataIC50: 141nMAssay Description:Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat#62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor sou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Pfizer

US Patent
LigandPNGBDBM186426(US9163021, 84 | US9163021, 230)
Affinity DataIC50: 18.1nMAssay Description:Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat#62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor sou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
Go to US Patent