BDBM18663 (2S)-3-(4-fluorophenoxy)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide::BMC185567 S-1::CHEMBL124718::Nonsteroidal AR Ligand, S-5

SMILES C[C@](O)(COc1ccc(F)cc1)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O

InChI Key InChIKey=KJMFOTCDISOHDX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 18663   

TargetAndrogen receptor(Rat)
Ohio State University

LigandPNGBDBM18663(CHEMBL124718 | BMC185567 S-1 | (2S)-3-(4-fluorophe...)
Affinity DataKi:  6.10nM ΔG°:  -10.4kcal/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Gtx

Curated by ChEMBL
LigandPNGBDBM18663(CHEMBL124718 | BMC185567 S-1 | (2S)-3-(4-fluorophe...)
Affinity DataKi:  6.10nMAssay Description:Agonist activity at androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Ohio State University

LigandPNGBDBM18663(CHEMBL124718 | BMC185567 S-1 | (2S)-3-(4-fluorophe...)
Affinity DataKi:  6.11nM ΔG°:  -10.4kcal/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2007
Entry Details Article
PubMed